Not necessarily. But it is often thought that the liver, evacuating in priority the ingested alcohol, would deal less well with the elimination of the drug and, as a result, would minimize the effectiveness of the treatment. A belief that has yet to be proven. On the other hand, skipping a tablet because you have planned a drunken evening certainly makes the treatment less effective. The alcohol/antibiotic mixture is particularly inadvisable in the event of a history of liver or kidney disease or epilepsy.
Frankly, not much. But antibiotics can cause nausea, vomiting or diarrhea, and high-dose alcohol… too. Therefore, chaining cocktails to taking antibiotics multiplies the risk of adverse effects, even amplifies them or accelerates their occurrence. Conclusion:to avoid a hangover, stay reasonable, ask your pharmacist for advice and read the instructions carefully before going out.
Thanks to Dr Catherine Huberman, general practitioner.